The Institute of Development Studies and Partner Organisations
Browse

A cost-effective particle agglutination assay to detect viral antibodies in dried blood spots: a simple solution to HIV and HCV screening

Download (242.16 kB)
journal contribution
posted on 2024-09-05, 23:29 authored by J.J. Jourbert
During the 1980s epidemiological data available on HIV indicated a low HIV seroprevalence in South Africa compared to the rest of Africa. In support of this, a study indicated a negative HIV incidence among adult Venda men and women diagnosed with sexually transmitted diseases. This correlated, at the time, with a negative incidence of HIV in the Kwa-Zulu region of South Africa. Other studies compared the incidence of HIV in Kwa-Zulu in 1985 and again in 1991. These authors reported an extremely low HIV statistical incidence (12/100 000) in 1985, but by 1991 the incidence of HIV in Kwa-Zulu had increased almost 200-fold, to 2 200/100 000. Nine years later, the situation was alarmingly different, with the South African Department of Health assessing that about 10% of the South African population was HIV positive. A rapid increase in HIV seroprevalence prompts the need for a simple, rapid and effective method of screening blood samples for epidemiological survey. A valid assessment of HIV seroprevalence is aided by unlinked anonymous screening — informed consent and councelling is not necessary — making use of simple but accurate assays. Trends in HIV seroprevalence can be determined by repeat surveys.

A CAJM HIV/AIDS survey.

History

Publisher

Central African Journal of Medicine (CAJM), University of Zimbabwe

Citation

Jourbert, J.J. [et al] (2003) A cost-effective particle agglutination assay to detect viral antibodies in dried blood spots — a simple solution to HIV and HCV screening, CAJM vol. 49, No. 11. Harare, Avondale: CAJM.,

IDS Item Types

Article

Copyright holder

University of Zimbabwe

Country

Gabon.; South Africa

Language

en

Identifier ISSN

0008-9176

Usage metrics

    University of Zimbabwe Social Sciences Research

    Categories

    No categories selected

    Keywords

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC