Association of Thirty-year Alcohol Consumption Typologies and Fatty Liver: Findings from a Large Population Cohort Study

Abstract

We report the association between 30-year drinking typologies and risk of fatty liver disease. People with sustained heavy drinking during midlife had greater risk of fatty liver than stable moderate drinkers at early old age. We also observed that sustained moderate drinkers did not have reduced risk of fatty liver compared to stable non-drinkers. These findings indicate that the drinking habits adopted by adults during midlife affect the development of fatty liver disease and cast doubt on the protective benefit of light-drinking.